Giuliana De Sio was born in Salerno and grew up in Cava de 'Tirreni, where her family originates from. De Sio's first public appearance was her when she was five in a show at the Teatro Verdi in Salerno. She moved to Terrasini when she was eighteen to live in a hippy commune before moving to Rome, where she befriended Teresa Ann Savoy and Alessandro Haber, who encouraged her to start acting. Her professional debut took place in 1976 when Gianni Bongiovanni chose her for Una donna. Elio Petri then gave her a part of her in Mani dirty di lei and Tonino Cervi chooses her to act in The Imaginary Sick with Alberto Sordi.
In the early 1980s she meets Massimo Troisi, who chooses her for an important role in her second film, Sorry for the delay (1982). She subsequently worked with Francesco Nuti in The Pool Hustlers (1982) and Casablanca Casablanca (1985).
Concetta De Nicola
Wanda Treptow
Self
Giulia Antinari
Concetta Melita 'Cetty' Saponero dal Puozzo
Self (archive footage)
Bigiù
Laura
Dr. Sophia Minardi
Irma Voglino
Maestrina dalla penna rossa
Annalisa Bottelli
Jessica
Tina
Alla Nazimova
Armida Casoni
Annalisa Bottelli Renzi Di Balsano
Rosario, the prostitute
Franca
Anna
Emanuela Setti Carraro
Erodiade
Chiara
Madre di Enzo
Self
Margherita
Luisa
Roberta
Emilia
Angelica
Chiara
Elena
Cesira
Teresa Capece
Self (archive footage)
Marta Vitale
Alix/Clara
Lara
Nagra
Iris
Sandra
Giulia Canella
Self
Elena Monti
Isabella Colbran
Capitana Quarantenni