Lizzy Caplan
Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble have earned her nominations at the Primetime Emmy Awards.
Her first acting role was on Freaks and Geeks (1999–2000). Since then, she has had series-regular roles in several television series, including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025).
Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023).
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Known for
The Simpsons
Virginia Johnson (voice)
Family Guy
Woman Arguing With Quagmire (voice)
American Dad!
Debbie (voice)
The League
Rebecca Ruxin
Childrens Hospital
Casey Klein
Childrens Hospital
Harmony
Smallville
Tina Greer
The Cleveland Show
Freaks and Geeks
Sara
True Blood
Amy
Masters of Sex
Virginia Johnson
Das Boot
Carla Monroe
New Girl
Julia Cleary
Angie Tribeca
Deirdre
Truth Be Told
Lanie Buhrman / Josie Buhrman
Zero Day
Alexandra Mullen
Castle Rock
Annie Wilkes
Fatal Attraction
Alex Forrest
Fleishman Is in Trouble
Libby Epstein
Tru Calling
Avery Bishop
Party Down
Casey Klein
Inside Job
Reagan Ridley (voice)
Mean Girls
Janis Ian
The Class
Kat Warbler
Now You See Me 2
Lula
Cobweb
Carol
Ill Behaviour
Nadia
The Interview
Agent Lacey
Undeclared
Beautiful Girl
Once and Again
The Pitts
Faith Pitt
127 Hours
Sonja Ralston
Cloverfield
Marlena
Allied
Bridget Vatan
Extinction
Alice
The Disaster Artist
Lizzy Caplan
Hot Tub Time Machine
April
The People We Hate at the Wedding
Marissa
Mr. Sunshine
Vivian Cornelli
Related
Marjee Sorelli
The Night Before
Diana
Crossing Over
Marla
My Best Friend's Girl
Ami
Bachelorette
Gena Myers
Orange County
Party Girl
Marvel One-Shot: Item 47
Claire Wise
3, 2, 1... Frankie Go Boom
Lassie
Late Night with Seth Meyers
Self
The Last Rites of Ransom Pride
Juliette Flowers
Save the Date
Sarah
High Road
Sheila
Conan
Self
7 Up & Me
Self
The Tonight Show Starring Jimmy Fallon
Self
Beef
Audrey
Watch What Happens Live with Andy Cohen
Self - Guest
Successful Alcoholics
Lindsay
The Sidekick
Bailey
Crashing
Jacqueline
Home for Actresses
Lizzy
From Where I Sit
Lily
Love Is the Drug
Sara Weller
Queens of Country
Jolene Gillis
Off Camera with Sam Jones
Self
The View
Self
Everybody's Doing It
Angela
Hardcore Action News
Lizzy Lyons
Drag
Chelsea
Self
The Last Leg
Self
The Toll Road
Emily
Close Up with The Hollywood Reporter
Self
Comedy Bang! Bang!
Self