Lizzy Caplan
Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble have earned her nominations at the Primetime Emmy Awards.
Her first acting role was on Freaks and Geeks (1999–2000). Since then, she has had series-regular roles in several television series, including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025).
Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023).
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Known for
Family Guy
Woman Arguing With Quagmire (voice)
The Simpsons
Virginia Johnson (voice)
American Dad!
Debbie (voice)
Smallville
Tina Greer
Childrens Hospital
Casey Klein
Childrens Hospital
Harmony
True Blood
Amy
The League
Rebecca Ruxin
Freaks and Geeks
Sara
Masters of Sex
Virginia Johnson
The Cleveland Show
New Girl
Julia Cleary
Angie Tribeca
Deirdre
Truth Be Told
Lanie Buhrman / Josie Buhrman
Castle Rock
Annie Wilkes
Zero Day
Alexandra Mullen
Das Boot
Carla Monroe
Fatal Attraction
Alex Forrest
Tru Calling
Avery Bishop
Party Down
Casey Klein
Fleishman Is in Trouble
Libby Epstein
Once and Again
Mean Girls
Janis Ian
The Class
Kat Warbler
Inside Job
Reagan Ridley (voice)
Now You See Me 2
Lula
The Interview
Agent Lacey
Cloverfield
Marlena
Ill Behaviour
Nadia
The Pitts
Faith Pitt
Cobweb
Carol
Undeclared
Beautiful Girl
127 Hours
Sonja Ralston
Hot Tub Time Machine
April
Allied
Bridget Vatan
Extinction
Alice
Mr. Sunshine
Vivian Cornelli
Related
Marjee Sorelli
The Disaster Artist
Lizzy Caplan
The People We Hate at the Wedding
Marissa
The Night Before
Diana
Crossing Over
Marla
Orange County
Party Girl
My Best Friend's Girl
Ami
Bachelorette
Gena Myers
Marvel One-Shot: Item 47
Claire Wise
Save the Date
Sarah
The Tonight Show Starring Jimmy Fallon
Self
Watch What Happens Live with Andy Cohen
Self - Guest
3, 2, 1... Frankie Go Boom
Lassie
Late Night with Seth Meyers
Self
The Last Rites of Ransom Pride
Juliette Flowers
High Road
Sheila
The Sidekick
Bailey
Beef
Audrey
From Where I Sit
Lily
Successful Alcoholics
Lindsay
Love Is the Drug
Sara Weller
7 Up & Me
Self
Conan
Self
Queens of Country
Jolene Gillis
Crashing
Jacqueline
The View
Self
Home for Actresses
Lizzy
Comedy Bang! Bang!
Self
Hardcore Action News
Lizzy Lyons
Everybody's Doing It
Angela
Drag
Off Camera with Sam Jones
Self
The Toll Road
Emily
Close Up with The Hollywood Reporter
Self
Chelsea
Self
The Last Leg
Self