Lizzy Caplan
Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble (2022) have earned her nominations at the Primetime Emmy Awards.
Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025).
Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023).
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Known for
The Simpsons
Virginia Johnson (voice)
Family Guy
Woman Arguing With Quagmire (voice)
Smallville
Tina Greer
American Dad!
Debbie (voice)
Now You See Me: Now You Don't
Lula
New Girl
Julia Cleary
True Blood
Amy
Castle Rock
Annie Wilkes
Childrens Hospital
Casey Klein
Childrens Hospital
Harmony
Angie Tribeca
Deirdre
Masters of Sex
Virginia Johnson
The League
Rebecca Ruxin
Truth Be Told
Lanie Buhrman / Josie Buhrman
Now You See Me 2
Lula
The Cleveland Show
Freaks and Geeks
Sara
Mean Girls
Janis Ian
Tru Calling
Avery Bishop
Inside Job
Reagan Ridley (voice)
Orange County
Party Girl
Cloverfield
Marlena
Party Down
Casey Klein
Zero Day
Alexandra Mullen
Drag
Crashing
Jacqueline
Das Boot
Carla Monroe
Fleishman Is in Trouble
Libby Epstein
The Interview
Agent Lacey
Once and Again
Queens of Country
Jolene Gillis
The Sidekick
Bailey
127 Hours
Sonja Ralston
My Best Friend's Girl
Ami
Fatal Attraction
Alex Forrest
Hot Tub Time Machine
April
Undeclared
Beautiful Girl
Allied
Bridget Vatan
Extinction
Alice
Cobweb
Carol
High Road
Sheila
The Class
Kat Warbler
Everybody's Doing It
Angela
The Disaster Artist
Lizzy Caplan
Mr. Sunshine
Vivian Cornelli
The Pitts
Faith Pitt
Related
Marjee Sorelli
7 Up & Me
Self
Crossing Over
Marla
Ill Behaviour
Nadia
The Night Before
Diana
Marvel One-Shot: Item 47
Claire Wise
Bachelorette
Gena Myers
The People We Hate at the Wedding
Marissa
The Last Rites of Ransom Pride
Juliette Flowers
Save the Date
Sarah
From Where I Sit
Lily
3, 2, 1... Frankie Go Boom
Lassie
Hardcore Action News
Lizzy Lyons
Beef
Audrey
Love Is the Drug
Sara Weller
Home for Actresses
Lizzy
Successful Alcoholics
Lindsay
The Toll Road
Emily
Watch What Happens Live with Andy Cohen
Self - Guest
The Tonight Show Starring Jimmy Fallon
Self
Late Night with Seth Meyers
Self
Conan
Self
The View
Self
Jimmy Kimmel Live!
Self
Jimmy Kimmel Live!
Self - Guest
Close Up with The Hollywood Reporter
Self
Off Camera with Sam Jones
Self
Chelsea
Self
Comedy Bang! Bang!
Self
The Last Leg
Self